Myocardial Uptake of 99m Tc-N-NOET and 201 Tl During Dobutamine Infusion
نویسندگان
چکیده
منابع مشابه
Myocardial perfusion imaging with technetium-99m-Tc NOET: comparison with thallium-201 and coronary angiography.
UNLABELLED We compared TcN-NOET [bis(N-ethoxy, N-ethyl dithiocarbamato)nitrido 99mTc] and 201Tl images to estimate the utility of this compound in the detection of coronary artery disease (CAD). METHODS Twenty-five patients undergoing cardiac catheterization had stress-redistribution-reinjection 201Tl SPECT imaging, stress-delayed (2, 4 and 6 hr postinjection) and rest-delayed (4 hr postinjec...
متن کاملComparison With Adenosine Stress
Background—The myocardial uptake of Tc-sestamibi is attenuated by dobutamine stress, resulting in underestimation of ischemia. N-Ethyl-N-ethoxy-dithiocarbamato-N-Tc (Tc-N-NOET) is a new Tc-labeled perfusion agent that is highly extracted by the myocardium by a mechanism different from that defined for Tc-sestamibi. We therefore hypothesized that Tc-N-NOET uptake would not be attenuated by dobut...
متن کاملLessons from the Tc-99m shortage: implications of substituting Tl-201 for Tc-99m single-photon emission computed tomography.
BACKGROUND In 2009, the Chalk River nuclear reactor closed for repairs that led to a critical shortage of technetium-99m (Tc-99m). Several centers used thallium-201 (Tl-201) as an alternative radiotracer for myocardial perfusion imaging. Because Tl-201 is considered by many as a suboptimal radiotracer, we sought to understand the impact of using Tl-201 (during the Tc-99m shortage) on downstream...
متن کاملPreparation of Tc 99m-Sn-thioglycolic acid-dl-isoleucine (Tc-99m-TGA-ILEU) complex and its comparison with Tl 201-chloride for myocardial imaging.
Dl-lsoleucine was complexed with Thioglycolic acid in the presence of Stannous ions to label with TC99m-Pertechnetate. Percentage labeling was determined by paper chromatography. Preparations of more than 95% labeled with Tc99m were injected to rabbits for imaging and tissue distribution studies. Tc99m.TGA.l LEU complex was investigated as a myocardial imaging agent with respect to its kinetics...
متن کاملTc-N-NOET Myocardial Uptake Reflects Myocardial Blood Flow and Not Viability in Dogs With Reperfused Acute Myocardial Infarction
Background—N-Ethoxy-N-ethyl-dithiocarbamato-nitrido-Tc (Tc-N-NOET) is a new neutral lipophilic Tc-labeled myocardial perfusion agent with a high first-pass extraction fraction and delayed redistribution kinetics after transient ischemia comparable to what is observed with Tl. It is unknown whether the uptake of this tracer reflects myocardial viability or just reperfusion flow in the setting of...
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ژورنال
عنوان ژورنال: Circulation
سال: 1999
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.100.15.1653